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KDIGO 2026 CLINICAL PRACTICE GUIDELINE FOR ACUTE KIDNEY INJURY (AKI) AND ACUTE KIDNEY DISEASE (AKD)
CHAPTER 1. AKI AND AKD DEFINITION, IDENTIFICATION, AND CLASSIFICATION
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1.1. Definition of AKI
Practice Point 1.1.1: Acute kidney injury (AKI) in children and adults is defined by the presence of one or more abnormalities of kidney function or structure known or presumed to have occurred within up to 7 days, in the appropriate clinical context (Table 1).
Agree
Disagree
Recommendation 1.1.1: We suggest using serum cystatin C to identify AKI in children and adults in clinical situations when serum creatinine (SCr) is less accurate (2B).
Agree
Disagree
Practice Point 1.1.2: A baseline SCr value should be ascertained for all patients with suspected or confirmed AKI.
Agree
Disagree
Practice Point 1.1.3: In adults, select the baseline SCr or cystatin C for an AKI episode using a hierarchical approach (Figure 1).
Agree
Disagree
Chapter 1.1 Comments
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