Post Test and Evaluation

Please note that to receive credit you must achieve a score of at least 70%.
Certificate of Credit will be emailed within 4 weeks of successful completion of the activity.

Post-Activity Test

Question Title

1. The presence of toxigenic C. difficile in the stool always indicates a C. difficile infection (CDI).

True

False

Question Title

2. Characteristics of the hypervirulent BI/NAP1/027 strain of C. difficile include all of the following except:

Production of Toxin A and Toxin B

High-level resistance to fluoroquinolones

Production of a metallo-beta-lactamase

Production of binary toxin

Question Title

3. Since the emergence and spread of the hypervirulent strain of C. difficile in the early 2000s, all of the following are true except:

A greater number of patients with CDI are undergoing colostomy or colectomy

The number of CDI infections in the community has increased

The mortality rate among the elderly (>65 years) with CDI has remained unchanged

The number of CDI cases in long-term care facilities has increased

Question Title

4. The use of which of the following antimicrobials poses the greatest risk for C. difficile infection?

Vancomycin

Cephalosporins

Carbapenems

Aminoglycosides

Question Title

5. Clinical study evidence has shown that the recurrence rate of an initial C. difficile infection following metronidazole or vancomycin treatment is approximately:

20%

50%

75%

Question Title

6. Patient factors that predict severe outcomes in CDI include all of the following except:

Older age

Lack of concomitant antimicrobial exposure

Elevated WBC

Elevated creatinine

Question Title

7. According to the current IDSA guidelines, first-line therapy for an initial episode of severe CDI is:

Metronidazole

Vancomycin

Probiotics

Rifaximin

Question Title

8. Clinical trials demonstrated that, compared to vancomycin, the use of fidaxomicin in the treatment of CDI resulted in significantly:

Higher overall clinical cure rates

Higher clinical cure rates for moderate-to-severe CDI only

Lower clinical cure rates in patients with mild infection

Lower rates of recurrent infection

Question Title

9. An effective treatment option for a patient with multiple CDI episodes is:

Nitazoxanide

C. difficile vaccine

Fecal microbiota transplantation

Probiotics plus metronidazole

Question Title

10. C.difficile infection recurrence is defined as a re-onset of symptoms plus:

Positive stool test for C.difficile

Positive test for presence of toxin

White blood cell count >10,000

Either Positive stool test for C.difficile or Positive test for presence of toxin