Neurobiology of Addiction

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* 1. Addiction is:

continued drug self-administration despite obvious harm to self and others

compulsive drug self-administration

drug craving

all of the above

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* 2. The five Cs of addiction are:

Chronic disease, impaired Control, Compulsive use, Continued despite harm, Craving

Craving, Chronic disease, Contextually based, Criminal, Confining

Compulsive use, Craving, Criminal, impaired Control, immune to Consequences

Craving, Criminal, Compulsive use, Cognitive dysfunction, Civilian

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* 3. Physical dependence is caused by up or down regulation of receptors on ________ systems.

hormonal

enzyme

neurological

all of the above

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* 4. Reward circuits are affected by:

all five senses

interpersonal relationships

both A and B

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* 5. The key neurotransmitter in the reward circuit is:

norepinephrine

topamax

dopamine

both A and C

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* 6. In drug-seeking behavior, animals develop ______________ self-stimulating behavior.

sensory

conditioned

stressful

all of the above

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* 7. Which of the following statements is not true?

Addictive drugs mimic all self-stimulatory behaviors

Any drug of abuse triggers drug seeking behaviors, independent of the original drug which caused the habit formation

All addictive drugs cause the release of dopamine in the reward center in the exactly the same way

Drugs will cause conditioned reinforcement and place preference

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* 8. Factors affecting addiction potential are:

agent

host

environment

all of the above

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* 9. Detox is:

impossible

dependent upon willingness

easy

too expensive for most people

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* 10. The best therapies for relapse prevention are:

physical therapies

regular detox

cognitive behavioral therapies

pharmacotherapies