Managing AMD and GA Progression: Insights from the AREDS & AREDS2 10-Year Follow-Up

Post-Test

COPE Course ID: 101219-TD
Activity Event Number: # xxx
Credit hours: 1.0 hour

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* 1. Contact Information (To receive credits)

Name

Address

E-Mail

OE TRACKER#:

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* 2. Which supplement combination in the original AREDS trial showed a 25% reduction in the risk of progression to late AMD?

Antioxidants plus zinc

Zinc and copper only

Vitamin C and beta-carotene

Omega-3 fatty acidsular surface damage only

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* 3. Why was beta-carotene removed from the AREDS2 formulation?

It lacked efficacy in reducing AMD progression

It was shown to cause liver damage

It increased the risk of lung cancer in smokers

It interfered with absorption of lutein

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* 4. According to the AREDS2 10-year follow-up study, which formulation showed sustained benefits in reducing progression to late AMD?

Original AREDS with beta-carotene

Placebo

DHA alone

Lutein/Zeaxanthin in place of beta-carotene

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* 5. Which dietary pattern was associated with reduced risk of AMD progression and slower GA lesion growth?

High protein diet

Low-fat American Heart Association diet

Mediterranean diet

Vegetarian diet

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* 6. For which group of patients is the AREDS formulation not recommended?

Patients with bilateral intermediate AMD

Current smokers

Patients with advanced AMD in one eye

Patients over 65 with mild cataracts

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* 7. Which of the following components of the Mediterranean diet was most associated with reduced risk of progression to GA

Nuts

Fish

Red wine

Whole grains

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* 8. What was the primary goal of the AREDS2 clinical trial?

To determine the impact of diet on AMD progression

To evaluate the role of intraocular injections in dry AMD

To test the addition of lutein/zeaxanthin and omega-3s to the AREDS formula

To compare surgical vs. pharmaceutical treatments for AMD

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* 9. Which statement best reflects the effect of AREDS2 supplements on GA?

AREDS2 supplements reverse GA

AREDS2 supplements reduce GA incidence and slow its expansion

AREDS2 supplements are only effective for neovascular AMD

AREDS2 supplements had no measurable effect on GA

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* 10. Which ocular characteristic is associated with faster geographic atrophy expansion?

Central foveal involvement

Small, single GA lesions

Multifocal GA configuration

Absence of drusen

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* 11. What role does patient counseling play in AMD management according to the presentation?

It is essential for discussing supplements and diet adherence

It should focus only on genetic risk factors

It is secondary to pharmaceutical intervention

It should be limited to surgical options