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Approaches to Target Priority Gram-negative Bacteria: Building a Better Toolbox
Activity Evaluation and Credit Application
Post Test
1.
Which of the following bacteria has been identified by the World Health Organization as a critical priority pathogen?
Methicillin-resistant
S. aureus
Carbapenem-resistant
P. aeruginosa
Fluoroquinolone-resistant
S. pneumoniae
Vancomycin-resistant
C. difficile
2.
Klebsiella pneumoniae
carbapenemase (KPC), which is endemic in the US, belongs to ambler class:
A
B
C
D
3.
Newer beta-lactamase inhibitors (e.g., avibactam, vaborbactam) are effective against all of the following beta-lactamases except:
ESBLs
KPCs
Metallo-beta-lactamases
Class A narrow-spectrum beta-lactamases
4.
In considering antimicrobial stewardship strategies, clinical studies have demonstrated the use of rapid diagnostic techniques in the clinical microbiology laboratory can result in all of the following except:
Earlier de-escalation of therapy
Decreased overall hospitalization costs
Decreased rates of MDR infections
Decreased hospital length of stay
5.
Resistance mechanisms commonly utilized by
Pseudomonas aeruginosa
include all of the following except:
Alterations to penicillin-binding protein
Production of quinolone dehydrogenase
Drug efflux pumps
Upregulation of beta-lactamase
6.
A fully synthetic fluorocycline under development that exhibits in vitro activity against
Acinetobacter baumannii
is:
Plazomicin
Eravacycline
Murepavadin
Relebactam