Approaches to Target Priority Gram-negative Bacteria: Building a Better Toolbox
Activity Evaluation and Credit Application

Post Test

Question Title

* 1. Which of the following bacteria has been identified by the World Health Organization as a critical priority pathogen?

Methicillin-resistant S. aureus

Carbapenem-resistant P. aeruginosa

Fluoroquinolone-resistant S. pneumoniae

Vancomycin-resistant C. difficile

Question Title

* 2. Klebsiella pneumoniae carbapenemase (KPC), which is endemic in the US, belongs to ambler class:

A

B

C

D

Question Title

* 3. Newer beta-lactamase inhibitors (e.g., avibactam, vaborbactam) are effective against all of the following beta-lactamases except:

ESBLs

KPCs

Metallo-beta-lactamases

Class A narrow-spectrum beta-lactamases

Question Title

* 4. In considering antimicrobial stewardship strategies, clinical studies have demonstrated the use of rapid diagnostic techniques in the clinical microbiology laboratory can result in all of the following except:

Earlier de-escalation of therapy

Decreased overall hospitalization costs

Decreased rates of MDR infections

Decreased hospital length of stay

Question Title

* 5. Resistance mechanisms commonly utilized by Pseudomonas aeruginosa include all of the following except:

Alterations to penicillin-binding protein

Production of quinolone dehydrogenase

Drug efflux pumps

Upregulation of beta-lactamase

Question Title

* 6. A fully synthetic fluorocycline under development that exhibits in vitro activity against Acinetobacter baumannii is:

Plazomicin

Eravacycline

Murepavadin

Relebactam