Despite improvements in technology, success rates following IVF treatment remain low (20 - 30% chance of having a baby per treatment). The main reason for the lower pregnancy rate is the poor quality of the embryos as a result of abnormalities in the chromosomes (termed embryo aneuploidy). Chromosomes carry genetic information and embryo aneuploidy is also the cause for miscarriages.
It has been suggested that testing the embryos by removing few cells (biopsy) and performing genetic testing, termed preimplantation genetic screening (PGS ), thereby replacing embryos without any chromosomal abnormalities (termed euploid embryos) may lead to higher success following IVF treatment. There have been recent progresses in embryo biopsy methods and genetic testing techniques making PGS safer than the old techniques. However, it is acknowledged that the effectiveness of PGS needs to be evaluated in well conducted studies before it is adopted.
We would be grateful if you could fill in the short survey towards helping us plan a study.