Diverse applications of nanopore technology: protein detection, microRNA screening

Nanopores are nanometer-scale apertures through which individual molecules can be translocated and probed electrically. Such sensors have proven to be versatile tools for detection and analysis, with the most prominent example being direct-read nucleic acid sequencing in the Oxford Nanopore platform. However, the value of the approach extends to diverse applications beyond sequencing. In this presentation, we will give a brief introduction to both protein and solid-state nanopores and the factors that are most critical to measurements with them. We will then describe a number of emerging applications that employ the platform and are currently being developed for translational use.

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