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Survey: A Clinical research Study of Tranexamic Acid for Heavy Menstrual Bleeding in Patients on Anticoagulants

A Clinical research study of Tranexamic Acid for Heavy Menstrual Bleeding in patients on anticoagulants

One in three women has heavy periods. Heavy periods can cause anaemia and poor quality of life for women. Heavy periods may be even worse for women taking oral or injectable anticoagulants. Anticoagulants are medications used to treat or prevent clots in the legs or lungs. Anticoagulants are tablets e.g Rivaroxaban, Apixaban, Edoxaban, Dabigatran and Warfarin or injections e.g Heparin, Dalteparin, Tinzaparin or Enoxaparin. Anticoagulation can be given for a few months or for life. Heavy periods may mean women and girls cannot go to work, school or social activities. Sometimes, the periods can be so heavy that these women and girls may need to go to Accident and Emergency or need a blood transfusion.

A tablet called Tranexamic acid can make heavy periods better. Tranexamic acid has not been tested in women with heavy periods who are taking anticoagulant tablets or injections. This is because there is a worry that Tranexamic acid may increase the risk of blood clots. There is lots of data though that shows Tranexamic acid does not increase the risk of blood clots in conditions which are high risk for clots such as pregnancy, after giving birth and when someone has been in a bad accident.

Is it important to you that research is done to see if Tranexamic acid is safe to use for women with heavy periods who take anticoagulants?

We would like to hear your opinions. Please complete this very short questionnaire - thank you!

Disclaimer: Although we have used the word women, we are including all people who menstruate or were assigned female at birth.

1.Have you ever taken anticoagulant tablets or injections (Apixaban, Rivaroxaban, Edoxaban, Dabigatran, Warfarin, Heparin injections)?(Required.)
2.What type of anticoagulant was it?
3.How long did you take the anticoagulant for?
4.Did you have heavy periods at any time when taking anticoagulants?
Note: A heavy period is defined as bleeding for more than seven days, passing clots larger than 2.5cm, needing to use two period products at once, changing your tampon or pad every one to two hours or flooding through clothes or bedding. If your menstrual bleeding is affecting your overall quality of life due to the flow, this is also defined as heavy bleeding.
5.Were you given treatment for heavy periods while taking the anticoagulants? (tick all that applies)
6.Did you need any other treatment for heavy periods while taking anticoagulants?
7.Have heavy periods stopped you living your normal life? (tick all that applies)
8.Please rate the negative impact heavy periods had on the quality of your physical health, work, mental health, general well being.
9.Do you think it is important to research the best treatment for heavy periods in those on anticoagulants?
10.Would you be willing to join a research trial for heavy periods in those taking anticoagulants? This would compare the effects of taking Tranexamic acid tablets and usual hormonal treatments against taking usual hormonal treatments alone?
11.Which of the reasons below do you think are important for doing a research study? (select as many as you want)
12.What is your age group?
13.What ethnic group do you belong?