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1. Which cancers did not see much benefit from the “one size fits all” combination chemotherapy approach to cancer?

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2. What does Dr. Slamon consider one of the most important steps forward in the treatment of cancer?

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3. What type of traditional treatment is used for tumors that are considered high risk?

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4. True or False: All cancer is genetic, but not all cancer is inherited.

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5. Some of the key hallmarks of cancer include:

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6. Which is the best description of the role of a CDK enzyme?

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7. True or False: Dr. Slamon’s lab found that palbociclib (a CDK-4/6 inhibitor) was most effective in triple-negative breast cancer.

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8. What is the most common subtype of breast cancer?

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9. What was the average difference in progression-free survival Dr. Slamon and his team found during the Phase II trial of patients receiving a CDK-4/6 inhibitor versus those receiving only standard of care?

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10. Major side effects of palbociclib differ from chemotherapy in which crucial way?

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