Atopic Dermatology Quiz Challenge

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* 1. Name

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* 2. Email Address

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* 3. Which of the following best describes the pathophysiology of atopic dermatitis (AD)?

Overproduction of sebum leading to clogged pores

An imbalance of inflammatory cytokines, including IL-4 and IL-13, leading to barrier dysfunction and immune dysregulation

A fungal overgrowth that triggers immune hypersensitivity

A genetic disorder affecting collagen production

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* 4. What is a key characteristic of mild to moderate atopic dermatitis?

Presence of widespread lichenification and fissuring

Red, inflamed, and pruritic skin with intermittent flare-ups

Pustular lesions with bacterial involvement

Non-pruritic lesions that heal without intervention

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* 5. Which of the following topical treatments is a PDE4 inhibitor approved for mild to moderate atopic dermatitis in patients aged 6 years and older?

Crisaborole

Tacrolimus

Roflumilast

Pimecrolimus

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* 6. What role does PDE4 inhibition play in atopic dermatitis treatment?

It directly increases collagen production for skin repair

It reduces inflammatory cytokines such as TNF-α, IL-4, and IL-13

It suppresses histamine release from mast cells

It eliminates Staphylococcus aureus colonization on the skin

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* 7. Which of the following is NOT a common comorbidity associated with atopic dermatitis?

Asthma

Allergic rhinitis

Hypertension

Food allergies

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* 8. Which patient group is at the highest risk for developing atopic dermatitis?

Adults over 50

Infants and young children

Postmenopausal women

Patients with a history of basal cell carcinoma

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* 9. In patients with atopic dermatitis, why is maintaining the skin barrier crucial?

It prevents excessive sebum production

It reduces epidermal water loss and protects against allergens, irritants, and microbial invasion

It increases skin cell turnover to prevent hyperpigmentation

It enhances absorption of systemic medications

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* 10. What is a key benefit of ZORYVE (roflumilast) in the treatment of atopic dermatitis?

It is a systemic therapy that targets the immune system

It provides rapid itch relief and reduces inflammation through PDE4 inhibition

It directly eliminates bacterial infections associated with AD

It is a corticosteroid that suppresses immune activity

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* 11. What is a common trigger for atopic dermatitis flare-ups?

Sun exposure

High-fat diet

Emotional stress and allergens

Excessive sweating without hydration

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* 12. Which of the following is a key goal of atopic dermatitis management?

Completely eliminate all triggers

Cure the condition with long-term antibiotic therapy

Reduce inflammation, restore the skin barrier, and minimize flare-ups

Use systemic steroids as first-line therapy