Thanks for being part of our community! We're excited to get your feedback on REGLAGENE, an innovator in the treatment in metastatic cancer, as we decide on our next investments.

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* 1. First, can you give us your email address again? We already have that in our email system but it's disconnected from this survey and we need it to connect the dots.

STEP 1: READ

Take a minute to read the description of REGLAGENE below.
Reglagene is developing a new oral medication for the treatment of life-threatening brain cancers, including glioblastoma and metastatic brain tumors. After initial discovery work at the University of Arizona supported by cancer research funding dollars the company is working to move those innovations Beyond Research to bring their innovative treatment to patients.

There are few effective treatment options available today for brain cancer patients.
  • The standard of care treatment available today is over 20 years old
  • Up to 30% of breast and lung cancer patients will get metastatic brain cancer.
  • Existing treatments are largely ineffective, highly toxic, and only extend life for a few months.
  • The average life expectancy for brain cancer patients is only 6 months post-diagnosis.
 The blood-brain barrier (BBB) limits the effectiveness of treatment
  • The BBB is a “filter” surrounding the brain that prevents toxins and medications from entering the brain
  • Therapeutics have to penetrate the BBB to get to brain cancer cells to be effective
  • Today’s treatments are administered intravenously and impact the whole body, leading to high toxicity at proper doses
 Reglagene’s new medications may be a more effective treatment for patients
  • They are proven to penetrate the BBB
  • They are well tolerated 
  • They are orally administered and better able to target cancer tumors
Their new medications have show great promise in animal tests
  • Their medications have shown the ability to penetrate the BBB, stop cancer growth and kill cancer cells
  • They have shown to be tolerable in high doses with little toxicity
Reglagene needs funding for the next stage and CANCER FUND is considering investing in the company
  • CANCER FUND initially invested in Reglagene in 2021 to help fund development and animal trials with good success
  • But significant work still needs to be done including finalizing their medicine and conducting expensive clinical human trials
  • The company is currently raising funds for that work to provide  effective, safer treatment for patients with primary and metastatic brain cancer
STEP 2: RATE

Please respond to the following questions with your own personal opinions so we can get honest, individual feedback.

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* 2. Would having treatment options like REGALGENE's oral medications give you more hope for the treatment of metastatic cancer?

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* 3. Do you feel that having treatment options like REGALGENE available would help you live with less fear of metastatic cancer?

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* 4. Do you believe this is the type of innovation that CANCER FUND should support?

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* 5. Do you think CANCER FUND should consider investing additional funds to support REGALGENE as they move to reach patients?

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* 6. Are you interested in investing or donating along with CANCER FUND to support REGALGENE's journey Beyond Research?

STEP 3: RAVE. OR RANT. OR NOT. (Optional)

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* 7. Do you any other thoughts you would like to share with us?

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