Excessive Daytime Sleepiness in Narcolepsy: Taking Steps to Improve Patient Quality of Life

Nevada Academy of Family Physicians
Winter Meeting

POST TEST

Cataplexy is pathognomonic of narcolepsy.

Cataplexy is a required finding for both Type 1 and Type 2 narcolepsy.

There are currently no FDA-approved medications to manage cataplexy.

Clinical studies have consistently demonstrated that amphetamines/methylphenidate are the most effective option in treating cataplexy.

Modafinil

Armodafinil

Solriamfetol

Pitolisant

Modafinil

Sodium oxybate

Lower-sodium oxybate

Pitolisant

Contains about half the sodium as traditional sodium oxybate

Not approved for the treatment of excessive daytime sleepiness

Requires twice-nightly dosing

Exhibited superiority to sodium oxybate in clinical trials