Quiz - Sessions 2 and 3

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* 1. Which of the following statements is not correct?

The infectious cycle and virus replication are synonymous

A susceptible cell has a functional receptor for a given virus

A cell that is resistant to infection has the viral receptor but is otherwise unable to replicate the virus

A permissive cell has the capacity to replicate virus

A susceptible and permissive cell is the only cell that can take up a virus and replicate it

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* 2. Which of the following statements about cytopathic effects (CPE) is correct?

Some viruses may not produce cytopathic effects in certain cells

Syncytium formation is a type of CPE

Rounding up and detachment of cultured cells is a type of CPE

Formation of a viral plaque depends upon CPE

All of the above

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* 3. Which of the following assays determines the number of infectious viral particles?

ELISA

Hemagglutination assay

Plaque assay

High throughput sequencing

Polymerase chain reaction

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* 4. If one million infectious virus particles are added to a culture dish of one million cells, which of the following will happen:

Each cell will receive one virus particle because the MOI is 1

None of the cells will receive any virus particles

37% of the cells are uninfected

Only one infectious cycle will take place

None of the above

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* 5. The results of which of the following experiments showed that nucleic acid contains genetic information:

The Hershey-Chase experiment with bacteriophage T2

A 1944 experiment with bacteria

The production of infectious DNA clones of viruses

Fraenkel-Conrat's work with TMV

All of the above

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* 6. How many different viral genome types are known?

Four

Seven

Ten

Six

Billions and billions

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* 7. The Baltimore scheme is useful for predicting the path from the viral genome to mRNA, but to do this a few other facts are needed. Which of the following is not one of these facts?

mRNA cannot be made from ssDNA

dsRNA can be directly translated into protein since it contains a (+) strand

A gapped dsDNA must be repaired before transcription can begin

Cells do not produce RNA-dependent RNA polymerase

None of these are incorrect