Activity Evaluation and Post Test

POST TEST

Question Title

1. An appropriate initial step for a patient newly diagnosed with C. difficile infection (CDI) is: (Required.)

Administer an oral fluoroquinolone

Institute contact precautions

Transfer to ICU

Test C. difficile strain susceptibility to vancomycin

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2. The most effective method to prevent the spread of C. difficile is: (Required.)

Regular washing of hands with soap and water

Regular use of alcohol-based hand sanitizers

Administer antimicrobial prophylaxis to any at-risk patient

Screen each patient admitted in the hospital for C. difficile colonization

Question Title

3. Since the emergence and spread of the hypervirulent strain of C. difficile in the early 2000s, all of the following are true except: (Required.)

A greater number of patients with CDI are undergoing colostomy or colectomy

The number of CDI infections in the community has increased

The mortality rate among the elderly (>65 years) with CDI has remained unchanged

The number of CDI cases in long-term care facilities has increased

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4. The use of which of the following antimicrobials poses the greatest risk for C. difficile infection? (Required.)

Vancomycin

Cephalosporins

Carbapenems

Aminoglycosides

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5. Clinical study evidence has shown that the recurrence rate of an initial C. difficile infection following metronidazole or vancomycin treatment is approximately: (Required.)

20%

50%

75%

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6. C. difficile infection recurrence is defined as a re-onset of symptoms plus: (Required.)

Positive stool test for C. difficile

Positive test for presence of toxin

White blood cell count >10,000

Either 1 or 2

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7. Patient risk factors for a recurrent infection include all of the following except: (Required.)

Older age

Absence of antimicrobial exposure

Presence of comorbidities

Decreased levels of serum IgG anti-toxin A

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8. According to the IDSA guidelines, first-line therapy for an initial episode of severe CDI is: (Required.)

Metronidazole

Vancomycin

Probiotics

Rifaximin

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9. Clinical trials demonstrated that, compared to vancomycin, the use of fidaxomicin in the treatment of CDI resulted in significantly: (Required.)

Higher overall clinical cure rates

Higher clinical cure rates for moderate-to-severe CDI only

Lower clinical cure rates in patients with mild infection

Lower rates of recurrent infection

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10. An effective treatment option for a patient with multiple CDI episodes is: (Required.)

Nitazoxanide

C. difficile vaccine

Fecal microbiota transplantation

Probiotics plus metronidazole

Question Title

* 1. An appropriate initial step for a patient newly diagnosed with C. difficile infection (CDI) is: (Required.)

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* 2. The most effective method to prevent the spread of C. difficile is: (Required.)

Question Title

* 3. Since the emergence and spread of the hypervirulent strain of C. difficile in the early 2000s, all of the following are true except: (Required.)

Question Title

* 4. The use of which of the following antimicrobials poses the greatest risk for C. difficile infection? (Required.)

Question Title

* 5. Clinical study evidence has shown that the recurrence rate of an initial C. difficile infection following metronidazole or vancomycin treatment is approximately: (Required.)

Question Title

* 6. C. difficile infection recurrence is defined as a re-onset of symptoms plus: (Required.)

Question Title

* 7. Patient risk factors for a recurrent infection include all of the following except: (Required.)

Question Title

* 8. According to the IDSA guidelines, first-line therapy for an initial episode of severe CDI is: (Required.)

Question Title

* 9. Clinical trials demonstrated that, compared to vancomycin, the use of fidaxomicin in the treatment of CDI resulted in significantly: (Required.)

Question Title

* 10. An effective treatment option for a patient with multiple CDI episodes is: (Required.)

1. An appropriate initial step for a patient newly diagnosed with C. difficile infection (CDI) is: (Required.)

2. The most effective method to prevent the spread of C. difficile is: (Required.)

3. Since the emergence and spread of the hypervirulent strain of C. difficile in the early 2000s, all of the following are true except: (Required.)

4. The use of which of the following antimicrobials poses the greatest risk for C. difficile infection? (Required.)

5. Clinical study evidence has shown that the recurrence rate of an initial C. difficile infection following metronidazole or vancomycin treatment is approximately: (Required.)

6. C. difficile infection recurrence is defined as a re-onset of symptoms plus: (Required.)

7. Patient risk factors for a recurrent infection include all of the following except: (Required.)

8. According to the IDSA guidelines, first-line therapy for an initial episode of severe CDI is: (Required.)

9. Clinical trials demonstrated that, compared to vancomycin, the use of fidaxomicin in the treatment of CDI resulted in significantly: (Required.)

10. An effective treatment option for a patient with multiple CDI episodes is: (Required.)