Signed, Sealed, Delivered: Evolving Treatment Options for the Management of Perianal Fistula in Crohn’s Disease Roundtable #2 ***Pre-Assessment*** Survey

Before you view the webinar, please take this pre-assessment. Taking this pre-assessment does not immediately qualify learners to earn credit. Certificates of credit will only be sent to learners who also receive a passing score on the post-test (separate from this survey), and fill out the evaluation form and application for credit.

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2.The addition of which of the following to an anti-TNF agent is associated with a higher rate of CPF healing vs the anti-TNF agent alone?

Ciprofloxacin

Mesalamine

Prednisone

Probiotic

3.A 25-year-old male with a recent diagnosis of CD presents with extreme perianal pain. A pelvic MRI is performed, leading to a diagnosis of CPF and abscess. Drainage of abscess and An examination under anesthesia is performed, during which a seton is placed in an intersphincteric fistula. The patient asks what to expect regarding his future course of therapy.

Which of the following is an appropriate response?

About one-third of patients experience treatment-refractory CPF

Antibiotic monotherapy is associated with a high rate of CPF healing

Thiopurines monotherapy is associated with high rate of CPF healing

The majority of CPF are healed with seton alone

4.A 42-year-old female with refractory CPF asks about the possibility of receiving mesenchymal stem cell (MSC) therapy on a clinical trial. What do you tell the patient is an important education point regarding MSCs?

MSCs are associated with a high risk of infection

MSCs are extracted either from a healthy, voluntary donor or the patient’s own fat tissue

MSCs are extracted several weeks before they are reinjected into the patient

MSCs are primarily obtained from the spleen

5.According to the 2022 proposed new Expert Consensus (published in The Lancet Gastroenterology & Hepatology, linked here), refractory CPF despite ostomy requiring proctectomy is considered which class?

Class 1

Class 2

Class 3

Class 4

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