CNV and New Pathogenic Models in Neurodevelopmental Disorders

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* 1. Please assess the Sessions overrall

  Strongly Disagree Disagree Neutral Agree Strongly Agree
Sufficient time was allowed for audience participation/active learning
The facilities were satisfactory
The session was free from commercial bias
Overall, I would rate this Symposium as excellent

Please assess each Speaker by their Session:

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* 2. Pathogenic CNVs, the adult phenotype, and counselling about long term outcome

Speaker: Anne Bassett 
Department of Psychiatry, University of Toronto, Toronto ON

Objectives: At the end of this session, participants will be able to:
1. Appreciate the important role of counselling about the adult phenotype of pathogenic copy number variations for individuals at different life stages
2. List three treatable conditions usually arising in adulthood associated with at least two different pathogenic CNVs
3. Describe potential benefits of genetic diagnosis for patients with schizophrenia, their families, and their clinicians

  Poor Fair Good Very Good Outstanding
Clarity of Voice
Met Stated Objectives
Balanced & Unbiased
Relevant to Practice Overall
Time for Active Learning

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* 3. The joy and pain of genetic counselling for recurrent CNVs implicated in neurodevelopmental disorders

Speaker: Melissa Carter 
Children’s Hospital of Eastern Ontario, Ottawa ON

Objectives: At the end of this session, participants will be able to:
1. Discuss the differences between a "syndrome" and a "susceptibility variant" with respect to recurrent CNVs
2. Understand one's own biases, and those in the case report literature, regarding these CNVs
3. Identify the gaps in the current evidence base for the pathogenic nature of these CNVs  
4. Share ideas about how to counsel our patients in the absence of certainty

  Poor Fair Good Very Good Outstanding
Clarity of Voice
Met Stated Objectives
Balanced & Unbiased
Relevant to Practice Overall
Time for Active Learning

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* 4. Gene Dosage effects on cognition and additive/oligogenic models in the neurodevelopmental clinic

Speaker: Sebastien Jacquemont
Hôpital Ste-Justine, Montréal QC

Objectives: At the end of this session, participants will be able to:
1. Understand the heritability of cognitive and behavioral traits
2. Understand the quantitative effects of genomic variants on cognitive and behavioral traits
3. Use available data to understand the contribution of genomic variants to the symptoms present in patients referred for a neurodevelopmental disorder.
4. Understand the implication of these studies on genetic counselling

  Poor Fair Good Very Good Outstanding
Clarity of Voice
Met Stated Objectives
Balanced & Unbiased
Relevant to Practice Overall
Time for Active Learning

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* 5. Gene Dosage effects on cognition and additive/oligogenic models in the neurodevelopmental clinic

Speaker: Melissa Carter 
Children’s Hospital of Eastern Ontario, Ottawa ON 

Objectives: At the end of this session, participants will be able to:
1. Understand the heritability of cognitive and behavioral traits
2. Understand the quantitative effects of genomic variants on cognitive and behavioral traits
3. Use available data to understand the contribution of genomic variants to the symptoms present in patients referred for a neurodevelopmental disorder.
4. Understand the implication of these studies on genetic counselling

  Poor Fair Good Very Good Outstanding
Clarity of Voice
Met Stated Objectives
Balanced & Unbiased
Relevant to Practice Overall
Time for Active Learning

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* 6. Copy Number Variants in Neurodevelopmental Disorders

Speaker: Christian Marshall 
The Hospital for Sick Children, Toronto ON 

Objectives: At the end of this session, participants will be able to:
1. Differentiate between recurrent and non-recurrent copy number variants and identify the mechanisms that lead to their formation.
2. Describe the strategies used for interpretation of copy number variants including the criteria used to establish clinical significance.
3. Identify the most common CNVs associated with neurodevelopmental disorders.

  Poor Fair Good Very Good Outstanding
Clarity of Voice
Met Stated Objectives
Balanced & Unbiased
Relevant to Practice Overall
Time for Active Learning

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* 7. As a result of attending this session, I am planning to:

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* 8. Please explain any changes you plan to make or personal learning projects you will pursue as a result of this session:

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* 9. Please indicate which CanMEDS roles you felt were addressed during this educational activity. (Select all that apply)

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* 10. General comments about individual speaker:

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* 11. What topics would you like to be addressed at future conferences to keep you up to date in your profession?

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