On behalf of the ASBMT Committee on Education we are pleased to introduce "Basic Principles and Practices of Hematopoietic Cell Transplantation and Cell Therapy – Question and Answer Approach,” a new feature highlighting a particular hematopoietic cell transplant and cell therapy quiz. Answers to each question appear with evidence-based “non-exhaustive” peer-review commentary.  Our aim is to provide you with a credible and freely available educational resource.  Questions generated and reviewed by Syed Abutalib, MD, Mark R. Litzow, MD, and William A. Wood, MD.  

* 1. Experiments and observations in which of the following animal species encouraged further trials of marrow grafting between human leukocyte antigen (HLA)-matched human siblings?

* 2. All of the following statements about hematopoietic stem cells (HSCs) are correct EXCEPT:

* 3. Which statement from the Guidelines of American Society for Blood and Marrow Transplantation (ASBMT) on indication for autologous and allogeneic hematopoietic cell transplant (HCT) is CORRECT?

* 4. All of the following statements about current uses of allogeneic hematopoietic cell transplantation (allo-HCT) by donor type in U.S. are true EXCEPT:

* 5. Which statement about trends of autologous hematopoietic cell transplants (auto-HCT) in U.S. by recipient age is CORRECT?