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Post Test and Evaluation Form
Please note that to receive credit you must achieve a score of at least 70%.
Certificate of Credit will be emailed within 4 weeks of successful completion of the activity.
Post-Activity Test
1.
The presence of toxigenic C. difficile in the stool always indicates a C. difficile infection (CDI).
(Required.)
True
False
2.
Characteristics of the hypervirulent BI/NAP1/027 strain of C. difficile include all of the following except:
(Required.)
Production of Toxin A and Toxin B
High-level resistance to fluoroquinolones
Production of a metallo-beta-lactamase
Production of binary toxin
3.
Since the emergence and spread of the hypervirulent strain of C. difficile in the early 2000s, all of the following are true except:
(Required.)
A greater number of patients with CDI are undergoing colostomy or colectomy
The number of CDI infections in the community has increased
The mortality rate among the elderly (>65 years) with CDI has remained unchanged
The number of CDI cases in long-term care facilities has increased
4.
The use of which of the following antimicrobials poses the greatest risk for C. difficile infection?
(Required.)
Vancomycin
Cephalosporins
Carbapenems
Aminoglycosides
5.
Clinical study evidence has shown that the recurrence rate of an initial C. difficile infection following metronidazole or vancomycin treatment is approximately:
(Required.)
5%
20%
50%
75%
6.
Patient factors that predict severe outcomes in CDI include all of the following except:
(Required.)
Older age
Lack of concomitant antimicrobial exposure
Elevated WBC
Elevated creatinine
7.
According to the current IDSA guidelines, first-line therapy for an initial episode of severe CDI is:
(Required.)
Metronidazole
Vancomycin
Probiotics
Rifaximin
8.
Clinical trials demonstrated that, compared to vancomycin, the use of fidaxomicin in the treatment of CDI resulted in significantly:
(Required.)
Higher overall clinical cure rates
Higher clinical cure rates for moderate-to-severe CDI only
Lower clinical cure rates in patients with mild infection
Lower rates of recurrent infection
9.
An effective treatment option for a patient with multiple CDI episodes is:
(Required.)
Nitazoxanide
C. difficile vaccine
Fecal microbiota transplantation
Probiotics plus metronidazole
10.
C.difficile infection recurrence is defined as a re-onset of symptoms plus:
(Required.)
Positive stool test for C.difficile
Positive test for presence of toxin
White blood cell count >10,000
Either Positive stool test for C.difficile or Positive test for presence of toxin
