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* 1. What are your main criteria for the selection of a VWF concentrate for the treatment of your patients with von Willebrand disease?

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* 2. What factors could prevent you from using a pure VWF concentrate?

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* 3. In patients with von Willebrand disease, what criteria do you use to assess whether the patient should be put on long-term prophylaxis or not?

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* 4. Any differences between adult and paediatric patients?

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* 5. - Before placing a patient on LTP, what PK parameters would you say are important for choosing the dose and frequency of injections?

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