1. Survey background & disclaimer

Doing clinical trials of neuroprotective therapies in people with progressive MS has proven difficult. At present there are no licensed therapies for progressive MS (secondary and primary progressive disease). This survey is being done to see whether or not people with MS are prepared to have three lumbar punctures as part of a clinical trial to assess whether or not neuroprotective therapies work in MS.

To complete this survey you first have to watch the accompanying YouTube video that is approximately 10 minutes long.

Please copy and paste the following URL into your web browser to watch the video:

http://www.youtube.com/watch?v=vOf7LF5Gb9E

* 1. Disclaimer

Although care has been taken in preparing the accompanying video and this survey, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, cannot be held responsible for any errors or omissions in the survey and accepts no liability whatsoever for any consequences arising from completing this survey. The University reserves the right to make changes to or take down this survey, or remove or alter any content at any time without notice. No third party will be given access to the data collected as part of this survey.

Professor Giovannoni welcomes comments and suggestions about this survey and the proposed study, which can be sent to him using the "additional comments " field at the end of this survey. Anyone wishing to contact him directly can do so using his contact details below.

Professor Gavin Giovannoni, Neuroscience & Trauma Centre, Blizard Institute of Cell and Molecular Science, 4 Newark Street, Whitechapel, LONDON E1 2AT

Tel: +44 20 7377 7000 / Email: g.giovannoni@qmul.ac.uk

I have read and understand the disclaimer and wish to proceed with this survey.

T