Managing the IBD Patient: C. difficle Pretest (ID: i783-11)

Upon completion of the pretest, please be sure to review the conversation, take the posttest, and proceed to https://integrityce.com/mondaynightibd/ to click Claim Credit in the top right corner to complete the evaluation form.

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* 1. Please list your last name and zip code:

Last name

ZIP/Postal Code

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* 2. What is your specialty?

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* 3. How many patients with IBD do you treat each week?

1 to 10

11 to 25

26 to 50

I am not directly involved in patient care

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* 4. Your patient, a 61-year-old female, presents to the emergency department with new onset watery diarrhea (5 BM/day), after she received ciprofloxacin for a urinary tract infection. You want to check her for C. difficile. Which of the following is the most clinically specific test for C. difficile?

Polymerase chain reaction (PCR) assay for toxigenic C. difficile gene

Enzyme immunoassay (EIA) for glutamate dehydrogenase (GDH)

Enzyme immunoassay (EIA) for the C. difficile toxin A/B

All three of them have similar specificity

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* 5. The same patient tests positive for C. difficile by GDH and EIA for toxin A/B. Which of the following treatment regimens is the first line therapy and gives her the best chance of clinical cure?

Vancomycin 125 mg four times/day for 10 days

Fidaxomicin 200 mg twice daily for 10 days

Vancomycin 125 mg four times/day followed by a taper and pulse

Either A or B