ADVANCED MANAGEMENT STRATEGIES FOR ALZHEIMER'S DISEASE

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If combined pharmacotherapy with a cholinesterase inhibitor (ChEI) plus an N-methyl-D-aspartic acid (NMDA) receptor antagonist appears to have no tangible beneficial effects, they should both be discontinued.
Current Alzheimer's disease research shows that promising disease-modifying therapies are on the horizon.
In my facility, management of agitation and aggression is the biggest challenge in patients with severe dementia.

Please choose the most appropriate answer:

Which of the following medications is most often associated with nightmares and vivid dreams?

Please indicate how you would manage the following scenario:

Mrs. S. is a 72-year old woman with moderate dementia. She has been on a ChEI and NMDA-receptor antagonist for 6 months. Family has not noted any improvement and her dementia is stable. She has not exhibited any signs of adverse effects from the medications. How would you counsel the family members about her current treatment?




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